Gene description for MAP2K1
Gene name mitogen-activated protein kinase kinase 1
Gene symbol MAP2K1
Other names/aliases CFC3
MAPKK1
MEK1
MEL
MKK1
PRKMK1
Species Homo sapiens
 Experiment description of studies that identified MAP2K1 in Mammary cancer-associated fibroblasts

1
Experiment ID1663
Identified moleculeProtein
Extracellular vesicle typeExosomes
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 34108659   
OrganismHomo sapiens
Experiment descriptionQuantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
AuthorsKugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R.
Journal name Nat Cell Biol
Publication year2021
SampleMammary cancer-associated fibroblasts
Sample namemCAF
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
mRNA
Methods used in the studyRT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
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